Zonal NePhRO scoring system

The zonal NePhRO scoring system is a kidney tumor complexity scoring system that was developed in 2013 by Tariq Hakky, Philippe Spiess, Wade Sexton, and Adam Baumgarten, from the Department of Genitourinary Oncology at H. Lee Moffitt Cancer Center & Research Institute in Tampa, Florida.
Development
It was developed because the few scoring systems previously available are complex and can be difficult to accurately measure data endpoints. The zonal NePhRO scoring system is a simpler tool that has been validated to predict the surgical complexity of a renal lesion before a patient undergoes partial nephrectomy. It was recently accepted into Clinical Genitourinary Cancer.
The development of a universal complexity scoring system is needed to facilitate inter-physician communication, better quantitate risk assessment among patients, and help characterize the likelihood of a perioperative complications with yearly litigation rates at 11% among urologists. The zonal NePhRO scoring system has contributed to the development of complexity scoring systems for renal tumor surgery. It is suspected to be more reproducible than the currently available scoring systems, making it a practical tool in clinical research and surgical practice.
Scoring
The zonal Ne.Ph.R.O. score is based on 4 anatomical components that are assigned a score of 1, 2, or 3 whose sum of these are used to classify renal tumor. Its variables include the (Ne)arness to collecting system, (Ph)ysical location of the tumor in the kidney, (R)adius of the tumor, and (O)rganization of the tumor. The Ne.Ph.R.O. score successfully predicted perioperative complications on both univariate and multivariate analyses (P=0.0008).

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