Bioline Reagents
Bioline Reagents is a primary manufacturer and developer of a wide range of specialised molecular biology products for the life science industry and research markets. Among the reagents it manufactures are ultra-pure nucleotides, DNA polymerases and mixes, DNA markers, competent cells, products for RNA analysis and other general reagents for molecular biology.
Bioline is one of only a very few primary manufacturers of ultra-pure nucleotides in the world, with 99.9% purity by HPLC analysis. Bioline developed a novel synthesis method for manufacture of 5’-Hydroxymethylcytosine (HMdCTP), the “sixth base” of the genome, important in the rapidly evolving field of epigenetics.
History
Bioline was established in 1992 and supplied enzymes for the Polymerase Chain Reaction (PCR) technology. Bioline offered a highly purified Thermophilus aquaticus (Taq DNA polymerase) as its first manufactured product and gradually expanded its range. Bioline now offers over 300 kits and reagents to the life sciences and molecular biology communities worldwide and is known as "The PCR Company", reflecting its focus on supplying reagents for the Polymerase Chain Reaction.
In July 2010, the company became a wholly owned subsidiary of Meridian Bioscience Inc. (NASDAQ: VIVO).
Locations and Facilities
Bioline is headquartered in London, UK and has international facilities in Berlin (Germany), Sydney (Australia), Singapore, Paris (France) and Taunton (USA).
- Bioline Reagents Ltd (London, UK) - Global Headquarters, research and development facilities and distribution hub
- Bioline GmbH, (Berlin-Brandenburg, Germany) - ISO 9001:2008 certified manufacturing facility in Luckenwalde Biotechnology Park
- Bioline (Aust) Pty Ltd (Sydney, Australia) - Marketing and sales, warehouse, manufacturing and R&D
- Bioline USA Inc (Taunton, USA) - Distribution hub, marketing and sales
- Bioline France (Paris, France) – Marketing and sales, opened Summer 2011
- Meridian Bioscience Pte Ltd (Singapore) - Subsidiary of Bioline Australia, opened Winter 2012
Product Areas
- Real-Time PCR Kits - SensiMIx and SensiFAST kits
- DNA Polymerases and Mixes - Accuzyme, Biotaq, Biolase, Bio-X-ACT Short, Immolase, MyFi, MangoTaq, MyTaq, RANGER DNA Polymerases and Mixes
- NTPs and dNTPs
- RNA Analysis and cDNA synthesis - Tetro reverse transcriptase, Tetro cDNA synthesis kit, MyTaq One-Step RT-PCR kit
- Nucleic Acid Isolation - ISOLATE II Kits for DNA and RNA extraction
- Competent cells and cloning reagents
- Molecular Weight Markers - HyperLadder and EasyLadder DNA markers, HyperPAGE protein markers
Distribution
Bioline has a rapidly growing distribution network in Europe, Latin America, Africa, the Middle East and Asia-Pacific. The combined Meridian/Bioline network of distributors currently totals over 100.
Custom, OEM and Bulk Manufacture
As a primary manufacturer Bioline provides customised, OEM and Bulk solutions to industrial and commercial partners.
Social Media
In 2010 Bioline launched a blog and also has a growing presence on social media networks including Twitter, Facebook, Linkedin and Youtube.