Lycée Jean-Mermoz is a senior high school/sixth-form college in Saint-Louis, Haut-Rhin, France, in the Basel-Mulhouse-Freiburg area. The school opened on 29 June 1958 and received its current building on 3 May 2008. It is the largest secondary school in the . L'Est Républicain described it as "un lycée comme une ville" (a lycee that is like a city). In 2024 the newspaper L'Alsace-Le Pays stated that the school had maintained stability. In 2023, there was also a similar number of students enrolled from the previous year, after previous student enrollment increases.