DASS-GUI is a stand-alone program written in and Qt that calculates and analyses all significant closed sets (cs closed itemsets "modules" = "patterns") of any given dataset containing host sets. The central data mining step, the cs calculation, has three distinctive features. It allows (i) efficient handling of multi-sets (same element might occur more than once in a set, a typical feature of biological data), (ii) selective calculation of only "meaningful" cs (in cases of too many cs), and (iii) calculation of the statistical significance of the identified patterns. The cs calculation can be done by either the DASS approach (with the unique features i and ii) or one of two other state-of-the-art algorithms (LCM and FPclose). The analysis mode allows additional filtering, calculation of pattern hierarchy, analysis of additional numerical features, enrichment analysis, module validation, easy handling of synonymous names, clustering and merging. Different export options allow easy usage of additional tools such as Cytoscape.
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