Sofie of Mecklenburg-Schwerin (disambiguation)

Sofie of Mecklenburg-Schwerin may refer to:

• Sofie of Mecklenburg-Schwerin (d. 1503), daughter of Duke Magnus II of Mecklenburg-Schwerin, who married to John, Elector of Saxony
• Sofie of Mecklenburg-Schwerin (d. 1631), daughter of Duke Ulrich III of Mecklenburg-Schwerin, who married to King Frederick II of Denmark