Raffaele A. Calogero

Prof. Raffaele A. Calogero is an associate professor at the University of Torino in the department of Molecular Biology and Health Science. He is also the President of the Italian Bioinformatics Society.
Education
Calogero received his graduation in Biological sciences from the Naples University in Italy, followed by his post-degree training at Institute of Genetics in the department of General and Molecular Biology from the same university. He received a fellowship from the Max Planck Institute for Molecular Genetics, Berlin, Germany.
Research and career
Calogero research interests include the development and optimization of analysis workflows and in mining transcription-based experiments, mainly in the oncology framework, and Single cell omics. His research on Microvesicles Derived from Mesenchymal Stem Cells Protect Against Acute Tubular Injury revealed that the mRNA transfer from MSCs to target cells via MV internalisation contributes to the regenerative function of MSCs, together with soluble factors, and may be utilised as a potential therapeutic method for regenerative medicine. He also conducted research on the Microvesicles produced from endothelial progenitor cells induce an angiogenic response in endothelial cells via a horizontal transfer of mRNA.
Calogero was a researcher at SORIN Biomedica S.p.A. Later, he was appointed as an Associate Professor of Molecular Biology at the University of Naples (Italy) in 1992 and went to the University of Turin in 1998.
Patents
Calogero obtained many patents for his inventions and his patents include
* Process to purify proteins from cell systems (EP0571337B1)
* Recombinant hepatitis delta antigen, process for the purification and use thereof (EP0485347A3)
* Procedure for the purification of proteins from cell systems (ITRM920385A1)
* Nucleic acid molecules encoding for chimeric cspg4 proteins and therapeutic uses thereof (US20190008940A1)
* Sequences that induce / stimulate the start of translation and their use (ITMI982733A1)
* Building of nucleic acid, vector and DNA vaccine including the same manufactured (ITTO20100028A1).
Publications
* Raffaele A Calogero, Cynthia L Pon, Maria A Canonaco, Claudio O Gualerzi. "Selection of the mRNA translation initiation region by Escherichia coli ribosomes". Proceedings of the National Academy of Sciences.
*Raffaele A Calogero, Cynthia L Pon, Claudio O Gualerzi. "Chemical synthesis and in vivo hyperexpression of a modular gene coding for Escherichia coli translational initiation factor IF1". Molecular and General Genetics MGG.
*Federica Cavallo, Guido Forni,. " Are oncoantigens suitable targets for anti-tumour therapy? ". Nature Review Cancer.
*Beccuti M, Cordero F, Arigoni M, Panero R, Amparore EG, Donatelli S, Calogero RA. "SeqBox: RNAseq/ChIPseq reproducible analysis on a consumer game computer". Bioinformatics.
*Christodoulou C, Spencer JA, Yeh SA, Turcotte R, Kokkaliaris KD, Panero R, Ramos A, Guo G, Seyedhassantehrani N, Esipova TV, Vinogradov SA, Rudzinskas S, Zhang Y, Perkins AS, Orkin SH, Calogero RA, Schroeder T, Lin CP, Camargo FD. " Live-animal imaging of native haematopoietic stem and progenitor cells". Nature.

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