The non-dialysis dependent chronic kidney disease (CKD), also abbreviated as NDD-CKD, is a designation used to encompass the status of those persons with an established CKD who do not yet require the life-supporting treatments for renal failure known as renal replacement therapy (including maintenance dialysis or renal transplantation). Relevant Terminologies The condition of individuals with CKD, who require either of the 2 types of renal replacement therapy (dialysis or transplantation), is referred to as the end-stage renal disease (ESRD). Hence, the start of the ESRD is practically the irreversible conclusion of the NDD-CKD. Relationship to CKD Staging Even though the non-dialysis dependent status refers to the status of persons with earlier stages of CKD (stages 1 to 4), patients with advanced stage of CKD (Stage 5), who have not yet started renal replacement therapy are also referred to as NDD-CKD. Epidemiology of NDD-CKD In the United States it is estimated that there are over 20 million people with NDD-CKD. As of 2011 the NDD-CKD is considered a major epidemic is virtually every developing or industrialized country throughout the world, and hence, an emerging pandemic. References See Also * chronic kidney disease * dialysis * end stage renal disease External Link * PubMed publications on NDD-CKD
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