Mahmoud Elfiky

Dr. Mahmoud Elfiky (born 15 December 1980) is an Egyptian Assistant Professor of Pediatric surgery at Qasr El Eyni Hospital, Cairo University. Dr. Mahmoud is well known for promoting Global Surgery and Pediatric Surgery through the years.
He has held position as board member at the World Federation of Associations of Pediatric Surgeons (WOFAPS) and International Pediatric Endosurgery Group (IPEG), international societies for paediatric surgery. He is an active member of other international pediatric surgical societies as the Egyptian Pediatric Surgery Association (EPSA) and the Pan African Pediatric Surgical Association (PAPSA). Mahmoud sits on the CDHi Medical Advisory Board; A global initiative to stop Congenital diaphragmatic hernia.
He is the active Webmaster for the WOFAPS, PAPSA and IPEG Middle East Chapter until this day.
He is currently serving as the Secretary of the Harvard Alumni Club Association of Egypt and is a Founding Faculty of the first Digital Campus Medical School in Europe.
Career
Dr. Mahmoud Elfiky gained his medical Doctor of Medicine degree (M.D.) at the Kasr Al Ainy faculty of Medicine Qasr El Eyni Hospital, Cairo University in 2009. In 2018, graduated from Global Clinical Scholars Research Training program from Harvard Medical School.
He received training as a Visiting Fellow at the Kinderkrankenhaus in Koeln, Germany in 2009. Followed by Great Ormond Street Hospital for Children NHS Foundation Trust in 2010. Dr. Mahmoud pursued a career in Transplant surgery as Affiliate Surgeon at the University of Nebraska Medical Center in Omaha, Nebraska and Visiting Surgeon at Cincinnati Children's Hospital Medical Center, Ohio, USA.
He then graduated from Harvard Medical School Global Clinical Scholars Training Program. Dr Mahmoud has shared in at least 6 international projects that yielded over 30 publications in Global Surgery and outcomes, with over 8 publications in the The Lancet journals that have awarded him for raising the ranking of Cairo University. The Lancet journal had an Impact factor of 79.321 for 2020 and is regarded as one of the most clinically relevant medical journals.
Dr Mahmoud was the country lead for many studies including DHREAMS along Prof. Wendy Chung from Columbia University Vagelos College of Physicians and Surgeons, Prof. Bruce Biccard from University of Cape Town for the ASOS, ASOS, ASOS Paeds projects, Dr. Naomi Wright from King's College London for the Global PaedSurg and more.
Dr Mahmoud is a peer reviewer of many Surgical Clinical Journals including Journal of Pediatric Urology and The Surgery Journal.
Outcomes of Publications
Dr Mahmoud's collaboration with the African Surgical Outcomes Study (ASOS) group Lancet publications have measured Perioperative outcomes of Surgeries in Africa and showed patients were twice as likely to die after surgery in Africa when compared with the global average for postoperative deaths. Following that, ASOS-2 study was launched all over Africa in 2019 and showed that enhanced postoperative surveillance for high-risk patients did not decrease in-hospital deaths or the incidence of severe complications in African surgical patients.
The ASOS research group studies also found out that Maternal mortality after caesarean delivery in Africa is 50 times higher than that of high-income countries and Neonatal mortality is double the global average. The advocacy for early diagnosis and appropriate management risk patients can improve maternal and neonatal outcomes in Africa.
Dr Mahmoud contributed to the GlobalSurg Collaborative study group Lancet Infectious Diseases paper that outlined that low human development index (HDI)countries carry a disproportionately greater burden of surgical site infections (SSI) than countries with a middle or high HDI and might have higher rates of antibiotic resistance resulting in higher Perioperative mortality. Further research from the same study group showed that using WHO Surgical Safety Checklist in emergency laparotomy was associated with a significantly lower deaths rate in surgical patients.
With the COVID-19 pandemic, subsidiary African COVID-19 Critical Care Outcomes Study (ACCCOS) research group studies were planned and executed, explaining tremendous data about COVID-19 outcomes in surgeries and critical care patients. Also, a Surgery Risk Calculator tool was developed to predict risk of severe postoperative complications in postoperative patients in Africa.
With his focus on Paediatric Surgery research, the results showed that Lower income countries had exponentially higher mortality among infants. Thus, calling for healthcare reform advocacy.
The resulting publications from the DHREAMS study group have found significant implicating genes in the development of Congenital diaphragmatic hernia (CDH) and Tracheoesophageal fistula in babies. The LONP1 (lon peptidase 1, mitochondrial) and ALYREF (Aly/REF export factor) genes were identified as CDH-associated genes. Results also identified MYRF gene as a new syndrome with a genetic overlaps with other developmental disorders. The study group discovered through Exome sequencing a Novel candidate genes in esophageal atresia/tracheoesophageal fistula and have acknowledged the researcher's from Cairo University contributions.

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