Hari Sharan Karki

Hari Sharan Karki is an American plant pathologist and microbiologist specializing in plant-microbe interactions, particularly focusing on rice and soybean pathogens. He has held research positions at Louisiana State University (LSU) and the United States Department of Agriculture (USDA).
Education
Karki earned a Master of Science (MS) degree in Plant Pathology and Crop Physiology from Louisiana State University in 2010. His master's thesis was titled "Physiological, biochemical and molecular characteristics associated with virulence of Burkholderia glumae: the major causative agent of bacterial panicle blight of rice". He continued his studies at LSU, completing a Doctor of Philosophy (PhD) in the same field in 2013 with a dissertation titled "".
Career
Karki has been involved in research roles at LSU and the USDA, focusing on understanding plant diseases and developing disease-resistant crop varieties. His work primarily addresses the challenges posed by bacterial pathogens affecting economically important crops such as rice and soybean.
In his doctoral research, Karki conducted a genetic study on the virulence mechanisms of B. glumae and rice resistance to BPB and sheath blight. He identified several regulatory elements involved in the pathogen's virulence, including sensor histidine kinase and response regulators. Additionally, he developed high-throughput methods for virulence testing using onion bulb scales as an alternative to rice panicles, facilitating more efficient preliminary assessments of pathogen virulence.
Beyond rice pathology, Karki has contributed to soybean and potato research. His work in soybean pathology involves identifying natural genetic diversity that confers resistance to various pathogens. In potato research, he has focused on resistance to Phytophthora infestans, the causative agent of late blight, identifying new sources of resistance in wild potato species.
Publications
Karki has authored and co-authored several scholarly works related to plant pathology and microbiology. His publications include detailed studies on the virulence mechanisms of Burkholderia glumae, the development of disease-resistant crop varieties, and the genetic basis of plant resistance to bacterial diseases.<ref name=":1" />
 
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