The Ground regulatory system is a system of rapid communication discovered largely by German medical researchers in the last half of the 20th C. existing within the body that is based on the extra-cellular matrix and controls various signals into and out of cells, influencing health and illness, and responsible for the maintenance of homeostasis. Background In 1953 a German doctor and scientist, Reinhold Voll, discovered that points used in acupuncture had different electrical properties from the surrounding skin, namely a lower resistance. Voll further discovered that the measurement of the resistances at the points came valuable indications as to the state of the internal organs. Further research was done by Dr. Alfred Pischinger, the originator of the concept of the 'system of ground regulation', as well as Drs. Helmut Schimmel, and Hartmut Heine, using Voll's method of electro-dermal screening. This further research revealed that the gene is not so much the controller but the repository of blueprints on how cells and higher systems should operate, and that the actual regulation of biological activities (see Epigenetic cellular biology) lies in a 'system of ground regulation'. This system is built on the ground substance, a complex connective tissue between all the cells, often also called the extra-cellular matrix. This ground substance is made up of 'amorphous' and 'structural' ground substance. The former is "a transparent, half-fluid gel produced and sustained by the fibroblast cells of the connective tissues" consisting of highly polymerized sugar-protein complexes. The smallest structural part of the ground substance is the matrisome, which has a polygon network structure of various layers of glyco-proteins and other proteins. The matrisome may be imagined as a series of identical line drawings placed one over the other, with each one a bit more rotated and further away than the last. This creates the appearance of hyperboloid spiraling tunnels through the many layers. The ground substance determines what enters and exits the cell and maintains homeostasis, which requires a rapid communication system to respond to complex signals(see Bruce Lipton). :This is made possible by the diversity of molecular structures of the sugar polymers of the ground substance, the ability to swiftly generate new such substances, and their high interconnectedness. This creates a redundance that makes possible the controlled oscillation of values above and below the dynamic homeostasis present in all living creatures. This is a kind of fast-responding, “short term memory” of the ground substance. Without this labile capacity, the system would quickly move to an energetic equilibrium, which would bring inactivity and death.<ref name=Frost /> There are four main systems of communication within the ground substance: biochemical, electrical impulses, electrochemical synapses and electromagnetic vibrations. Information flows as chemical, electrical, magnetic and bio-energetic signals from the body: the 'how to' instructions from the genes into the ground substance and the 'what to' instructions from the ground substance to the cells. The nervous system extends into the ground system, but there are no synapses, so the control of cells occurs through the biochemical medium of the ground substance via neurotransmitters, neuropeptides and cytokines. Fine hollow tubes within the cells (aquaporins) and cell membrane 'receptors' carry the biochemical signals into and out of the cells. Biochemicals released by the nerve endings also are involved in the inflammatory process via the mast cells, or 'the guards of the ground substance.' The mast cells also interact with the terminal axons of the autonomic nervous system and sensory signals from the ground substance signal the CNS to stimulate the release of various chemicals and hormones. Pollution, poor nutrition or any internal toxins not properly disposed of can change the biochemistry of the ground substance so that signals are distorted. :For its biochemical survival, every organism requires the ability to rapidly construct, destroy and reconstruct the constituents of the ground substance.<ref name=Frost /> Between the molecules that make up the ground substance there are minimal surfaces of potential energy. The charging and discharging of the materials of the ground substance cause 'biofield oscillations' (photon fields). The interference of these fields creates short lived (from 10-9 to up to 10-5 seconds) tunnels through the ground substance. :Through these tunnels, shaped like the hole through a donut, large chemicals may traverse from capillaries through the ground substance and into the functional cells of organs and back again. All metabolic processes depend upon this transport mechanism.<ref name=Frost /> Major ordering energy structures in the body are created by the ground substance, such as collagen, which not only conducts energy but generates it, due to its piezoelectric properties. :Like quartz crystal, collagen in the ground substance and the more stable connective tissues (fascia, tendons, bones, etc.). transforms mechanical energy (pressure, torsion, stretch) into electromagnetic energy, which then resonates through the ground substance (Athenstaedt, 1974). However, if the ground substance is chemically imbalanced, the energy resonating through the body loses coherence.<ref name=Frost /> This is what occurs in the adaptation response described by Hans Selye. When the ground regulation is out of blaance, the probability of chronic illness increases. Research by Heine indicates that unresolved emotional traumas release a neurotransmitter substance P which causes the collagen to take on a hexagonal structure that is more ordered than their usual structure, putting the ground substance out of balance, what he calls an "emotional scar"providing "an important scientific verification that diseases can have psychological causes."<ref name=Frost /> (see also Bruce Lipton) Organisms are open, highly networked systems with rhythmic pulsations such as biorhythms, and non-linear which makes them capable of self-organization, in a context of ordered structure or determined chaos, as, like laser light, they contain phase and frequency-identical bundles of energy. The ground substance like the human organism as a whole vibrates between 7 and 10 Hz, or the main Schumann frequency. Unlike physical networks, which fail when a component fails, the bio-sensor network in the ground substance can have many parts fail, but the function is maintained, though at a lower level. "Thus, even under duress, the bio-sensor network allows the ground substance to continually make small “when-then” type adjustments to maintain bodily homeostasis. When such a system has suffered partial debilitation, internal repair mechanisms or external therapy can usually return it to full function." (Frost) The transfer of energy within the ground substance allows for the almost instantaneous transfer of information or signals throughout the body. " The functions of the ground substance form a system of regulation for the whole body. "<ref name=Frost />
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