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Factoryase
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A Factoryase is any one of many types and sizes of biomolecular megastructures: The Importance of their immense atomic mass - that provides them with their immense biochemical powers of creation and manipulation - is successfully challenged by the 'Lilliputian' nature of the even more immense quantity of ambiguous co factors. Examples : first, the 'ases', this suffix denotes an enzyme: Helicase, replicase, isomerase, topoisomerase, swivelase, synthetase, polymerase, Examples : next, the 'somes' denotes a large factoryase: replisome, primosome, spliceosome, ribosome, Examples : others: DnaB, unwinding; DnaG, a primase ; An example of the general functions of a factoryase, in general : "Binding of _ to _ changes the conformation of the site on _ that binds to the _ and as a result _ now has a high affinity for _ . This enables _ to bind, and this is the means by which _ is brought to _ . <1 p487> |
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