Difference between Indica and Sativa

Indica plants are generally present in Central Asia, whereas the Sativa has been found to grow mostly near the equator. The Indica is not only abundant throughout the world but also grows faster than the Sativa.
Sativa has been observed to give users a feeling of mild euphoria just where the user remains in his senses without letting go of the reality. Indica on the other hand, completely takes the user on a higher euphoria where the user cannot make sense of reality or the hallucinations. In more slang terms, the Sativa gets the user “high”, whereas the Indica gets the user “stoned”. Indica is used more for medicinal purposes whereas the sweet smelling smoke of the Sativa is preferred by habitual smokers looking for a good time.
Indica/Sativa chemotaxonomy ratio
Sorted by ratio
Phytocannabinoids
* THC (Δ -tetrahydrocannabinol): 5.6:1, most psychoactive cannabinoid in Cannabis.
* CBD 1:4
** THC specific
*** THC inhibitor: An isomer of THC who blocks THC itself
*** Decrease social isolation induced by THC
*** Cannabidiol may block THC's interference with memory
** Anxiolytic: Reduces anxiety in social anxiety disorder
** Atypical antipsychotic. Effective in treating schizophrenia. Also, THC may cause schizophrenia-like symptoms.
** May relieve symptoms of dystonia
** Disputed
*** Sedative: It has displayed sedative effects in animal tests. Some research, however, indicates that CBD can increase alertness
* CBC 1:1, may contribute to the overall analgesic effects
* CBN ?:?: A metabolite of THC, cause drowsiness.
Non-psychoactive phytocannabinoids
* CBG: 1.3:1, cannabigerol has been found to act as a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist
* CBDV+THCV. THCV has been shown to be a CB<sub>1</sub> receptor antagonist, i.e. it blocks the effects of THC.
Other non-psychoactive biochemicals
* α-Humulene,, odorant
* α-Terpinene
* Myrcene Indica is typically best for nightime use while Sativa is preffered daytime by most users.
Medical and dependency potential
One diagnostic criteria for DSM-IV is "Characteristic withdrawal symptoms from the substance, such as insomnia or difficulty falling asleep, cravings, restlessness, loss of appetite, difficulty concentrating, sweating, mood swings, raise in temperature, depression, irritability, and anger." Indica is more infamous than Sativa of the described symptoms. In fact, the a sativa-dominated Cannabis strain Jack Herer, is effective in relieving anxiety, nervousness, stress and depression. It is also viewed as a motivational medicine, stimulating energy, creativity and concentration. Jack Herer is well known for both its cerebral high and its strong body high.

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