Annie Kathuria

Annie Kathuria is an American neuroscientist who works at Harvard Medical School, psychiatry department, as an Instructor of Investigation. She is affiliated with Chemical Biology and Therapeutics Science at the Broad Institute, Massachusetts General Hospital and Harvard Stem Cell Institute.
Education
Kathuria did a double major in Neuroscience and Genetics Cell Biology and Development at the University of Minnesota. Then she completed a Master of Science and a PhD from King's College London. During her time in her PhD she trained under Jack Price, Fiona Watt, and Simon Baron Cohen.
Selected publications
* “Stem Cell “MINI-BRAINS” for studying the Biology of Bipolar Disorder” published on September 9, 2020, on Genome Medicine. Kathuria was a postdoctoral research fellow in Center for Genomic Medicine, Massachusetts General Hospital. In her study, she initiated pluripotent stem cells (iPSCs) were produced from skin cells from patients with bipolar disorder (BPD) and solid control subjects, which were at that point utilized to form cerebral organoids, three-dimensional neuronal culture frameworks that summarize the advancement of the human forebrain.
* “Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia” by Annie Kathuria.
* Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development, published in 2018. Through this study, Dr. Kathuria established a robust method of generating stem cells from hair cells and found a viable therapeutic target for treating autism caused neurological deficits using gene therapy.
* “Distinct effects of interleukin-6 and interferon-? on differentiating human cortical neurons” published in April 2022. In this publication, she has found a potential drug for the treatment for the oxidative stress frequently reported in schizophrenia. Such work serves as the basis for larger clinical trials and represents a viable therapeutic agent against this devasting disorder.
Awards and honors
On January 17, 2020 Kathuria received NARSAD Young Investigator Award from Brain and Behavior Research Foundation.

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