Sigma anti-bonding molecule calcium carbonate

Sigma anti-bonding molecule calcium carbonate is a type of Calcium carbonate that is produced with a very specialized process, using natural Canadian small oyster shells as basic raw material. This Calcium carbonate has a Sigma Anti-Bonding Molecule, a weak bonding force which is more easily soluble and absorb into the cell. Active Calcium Ca++ is produced from SAC during metabolism in the body and has a powerful functions on stimulation and metabolism in our body and this results in healthier metabolic system and stronger bone structure. Cell structure as well
Chemistry
CalciumCarbonate is poorly soluble in pure water (47 mg/L at normal atmospheric CO2 partial pressure as shown below).
The equilibrium of its solution is given by the equation (with dissolved calcium carbonate on the right):
where the solubility product for [Ca2+] is given as anywhere from Ksp 3.7×10−9 to Ksp 8.7×10−9 at 25 °C, depending upon the data source
But SAC is more soluble compare to general calcium carbonate in pure water ( 1250mg/L at normal atmospheric CO2 partial pressure as shown below).
The equilibrium of its solution is given by the equation (with dissolved calcium carbonate on the right):
Preparation
Sigma anti bonding calcium carbonate(Solid) is prepared from calcium carbonate under high strong magnetic field, high electronic voltage after pretreated in liquid nitrogen. SAC( solid) is a very instability in atmosphere. SAC become a calcium carbonate again as soon as exposure on the air.
Water Ionization by SAC
The Ionic Product
Kw is very Calcium ion dependent, increasing with SAC concentration.
Sigma Anti-bonding Calcium and Osteoporosis
Calcium is the most abundant mineral for the activation of cells and metabolism in the body and is found in some foods, added to others, available as a dietary supplement, and present in some medicines (such as antacids). Calcium is required for vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling and hormonal secretion, though less than 1% of total body calcium is needed to support these critical metabolic functions . Serum calcium is very tightly regulated and does not fluctuate with changes in dietary intakes; the body uses bone tissue as a reservoir for, and source of calcium, to maintain constant concentrations of calcium in blood, muscle, and intercellular fluids. However, intracellular calcium ion is strictly controlled in nano-molar concentrations, because disruption of calcium homeostasis triggers cytotoxicity through activation of Ca++ - dependent enzymes and cell death programs. In the present study, blood calcium level increased in parallel with the concentration of SAC in the drinking water. Notably, feeding for Rat, 250g body weight only 0.0012% of SAC(0.12% solution, 1200ppm calcium) in drinking water was similar to 0.07% of sericin conjugated calcium( 10% solution) in the improvement of osteoporosis in ovariectomized rats, indicating a higher absorption rate of SAC. Such a high absorptive property of SAC may be due to its weak bonding force with other molecules. 0.0012%of SAC solution is a very small intake quantity. It is 2.5mg-5mg of calcium /day/60kgs human body weight
The remaining 99% of the body’s calcium supply is stored in the bones and teeth where it supports their structure and function.. Also, osteoporosis is a major age-related health problem for men and women who often have negative calcium balance due to decrease in intestinal calcium absorption, insufficient dietary calcium intake, as well as increase in urinary Calcium loss associated with estrogen deficiency during menopause . The main underlying cause of fractures in osteoporosis is increased bone fragility as a result of bone loss. Fracture risk is determined by absolute bone mineral density (BMD), regardless of age . Low BMD is realized to the most important risk factor that can lead of osteoporosis .
According to clinical animal trial , Therapeutic Effects of Sericin-calcium and Sigma
Anti-bonding Molecule Calcium Carbonate on Osteoporosis in Ovariectomized Rats , Sac Calcium with actual intake calcium quantity is 292times more powerful than Sericin conjugated calcium to absorb into the bone cell.
Values of Bone Metabolism Index Test
Values are mean ± SD for 5 rats. Means with different superscript letters are significantly different at p<0.05 by
Duncan’s multiple range tests. Sham; sham operation, OVX; no-treatment after ovariectomy, OVX+SC; SC
treatment after ovariectomy, OVX+SAC; sigma anti-bonding calcium treatment after ovariectomy.
Images for bone mineral density of femur ovariectomized rats.
Bone mineral density measurement values
Values are mean ± SD for 5 rats. Means with different superscript letters are significantly different at p<0.05 by
Duncan’s multiple range tests. Sham; sham operation, OVX; no-treatment after ovariectomy, OVX+SC; SC treatment after ovariectomy, OVX+SAC; sigma anti-bonding calcium treatment after ovariectomy.
Values of breaking force and bone mineralization measurement
Values are mean ± SD for 5 rats. Means with different superscript letters are significantly different at p<0.05 by
Duncan’s multiple range tests. Sham; sham operation, OVX; no-treatment after ovariectomy, OVX+SC; SC treatment after ovariectomy, OVX+SAC; sigma anti-bonding calcium treatment after ovariectomy.
Health and Dietary Applications
Calcium carbonate is widely used medicinally as an inexpensive dietary calcium supplement or gastric antacid but there are so many problems with much quantity intake. Excess calcium from supplements, fortified food and high-calcium diets, can cause the milk-alkali syndrome, which has serious toxicity and can be fatal(12, 13, 14). Calcium has been added to over-the-counter products, which contributes to inadvertent excessive intake. Excessive calcium intake can lead to hyperkalemia, complications of which include vomiting, prostate cancer, abdominal pain and altered mental status. But Sigma anti bonding calcium carbonate is the best key to solve these problems with tiny quantity of 1/100-1/200.
SAC and Human Kinetics
SAC Calcium is very effective to improve significantly the Instantaneous speed and the dynamic force of muscle in locomotion. According to the swim trials, the speed of swimmers who intake SAC were not only more fast to compare with pretest( control) but also decreased the lactate level.

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