Replicationdomain

ReplicationDomain is an online database resource for storing, sharing and visualizing DNA replication timing and transcription data, as well as other numerical epigenetic data types. Data is typically obtained from DNA microarrays or DNA sequencing. The site has a user registration system and registered users are allowed to upload their own data sets. Non-registered users may freely view and download public data sets, registered users may upload their own data sets and view them privately, share their data sets with other registered users, or make their data sets publicly available. In addition users can restrict sharing of their data sets to a user designated group of registered users.
History
The ReplicationDomain online database was envisioned by Dr. David Gilbert before his hiring at Florida State University in late 2005. Work on the project was started in early 2006 and by August 2006 the first prototype, supporting only Mus Musculus species data, was online. Since those humble beginnings the site has added support for additional species data, support for additional epigenetic data types and granular support for sharing data sets with registered users. The ReplicationDomain staff in August 2006 was David Gilbert (Director), Alexander Stuy (System architect, database design and administrator, backend programmer), Nodin Weddington (Front end user interface programmer, database programmer, database design), Ichiro Hiratani (Interface designer, consultant, tester) and Tyrone Ryba (Interface designer, consultant, tester).
Funding
ReplicationDomain is funded by NIH:
"Genome Plasticity During ES Cell Differentiation to Neural Lineages".
Principle Investigator: David M. Gilbert, PhD.
Agency: NIH.
Type: RO1 (1R01GM083337-01A1).
Period: 9/30/07 - 8/31/11 Total Costs: $1,100,000.
Data Sets
As of May 2010 the ReplicationDomain database holds 138 data sets: 77 Mus Musculus data sets, 41 Homo Sapiens data sets and 20 Drosophilia data sets, with a total of 112,019,466 separate data points. The site also supports Schizosaccharomyces data sets, but as of May 2010 no such data sets have been uploaded.
Site Usage Documentation
* General Navigation (Video)
* Uploading Data Sets (Video)

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