Phytoserm

PhytoSERM (phyto plant, SERM selective estrogen receptor modulator) are botanically derived substances that possess SERM qualities, similar to synthetically manufactured drugs of the same category.
Mechanism of action
Similarly to SERMs, phyto-SERMs act on the estrogen receptor in a selective manner, either as agonists, or as antagonists, thereby granting the possibility to selectively stimulate or inhibit estrogen-like responses in different tissues. The molecular basis for this discrimination lies in the variability of transcription coregulators in different tissues which interact with the estrogen receptor. Furthermore many phytoestrogen (including phyto-SERMs) appear to be somewhat selective in binding for the estrogen receptor beta (ERβ) compared to the estrogen receptor alpha (ERα) . These two forms of the estrogen receptor display somewhat different tissue distributions and regulate a partially overlapping set of genes.
PhytoSERMs' unique mechanism of action, being able to target specific tissues precisely while unaffecting others, may make them safer candidates for treatment of estrogen deficiencies.
Category members
* - a phytoSERM used for the treatment of menopause symptoms and bone health
Indications
PhytoSERMs are suitable for treating estrogen deficiencies that cause menopause symptoms, osteopenia and osteoporosis.

Main Menu

See Also

Main Menu