Pascale Guiton

Pascale Guiton is an assistant professor and researcher in the Department of Biological Sciences at California State University, East Bay. She also received the William S. Kell Presidential Award for Academic Excellence. After that, she earned her Ph.D. in Biological Sciences and Medicine at Washington University in St. Louis in 2012, where she was part of the Edward A. Bouchet Graduate Honor Society. She completed a Postdoctoral Fellowship at the Stanford University School of Medicine from 2012 to 2017, where she worked in the lab of John C. Boothroyd. Guiton is also the Principal Investigator of a research lab, which studies Toxoplasma gondii, one of the most commonly found parasites in humans. Her research has been published in several peer-reviewed journals, including Infection and Immunity, mBio, Antimicrobial Agents and Chemotherapy, and PLOS One. Her publications "Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infection" and "Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections" were both selected as articles of significant interest in the journal issues in which they were published. Guiton believes that educators and scientists should not shy away from potentially controversial topics, as they are necessary for students to recognize the biases and cultural contexts that inform research and science curriculum. The aim of this document is to provide educators with information on the discoveries and achievements of Black scholars, which can then be integrated into in their course content. Through her work with ABC, Guiton has co-authored "Designing an Anti-Racist Syllabus" and "Anti-Racist Educator's Starting Guides." Guiton, along with other faculty members at CSU East Bay, previously spoke out against an economics professor for teaching a theory that race influences intelligence. During a meeting of the CSU East Bay Board of Trustees, Guiton objected to this teaching by saying that this professor "asserts in his work that people of sub-Saharan African descent, people like me and many of our students, have significantly lower IQs than any other ethnicity."
* Guiton PS, Sagawa J, Fritz H, JC Boothroyd. An in vitro model of intestinal infection reveals a developmentally regulated transcriptome of Toxoplasma sporozoites and a NF-κB-like signature in infected host cells. PLoS One. 2017 Mar 31;12(3):e0173018.
* Guiton PS, Hannan TJ, Ford B, Caparon MG, Hultgren SJ. Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections. Infect. Immun. 2013 81(1):329-39.
* Frank KL, Guiton PS, Barnes AM, Manias DA, Chuang-Smith ON, Kohler PL, Spaulding AR, Hultgren SJ, Schlievert, PM, Dunny GM. AhrC and Eep are biofilm infection-associated virulence factors in Enterococcus faecalis. Infect. Immun. 2013 81(5):1696-708.
* Guiton PS, Cusumano CK, Kline KA, Dodson KW, Han Z, Janetka JW, Henderson JP, Caparon MG, Hultgren SJ. Combinatorial small-molecular therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob. Agents Chemother. 2012 56(9):4738-45.
* Nielsen HV, Guiton PS, Kline KA, Port GC, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ. The metal ion-dependent adhesion site motif of EbpA pilin mediates pilus function in catheter-associated urinary tract infection. Mbio. 2012 3(4):e00177-12.
* Guiton PS, Hung CS, Hancock L., Caparon MG, Hultgren SJ. Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infection. Infect. Immun. 2010 78(10):4166-4175.
* Guiton PS, Hung CS, Kline KA, Roth R, Kau AL, Hayes E, Heuser J, Dodson KW, Caparon MG, Hultgren SJ. Contribution of autolysin and sortase A during Enterococcus faecalis DNA-dependent biofilm development. Infect. Immun. 2009 77(9):3626-38.

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