Main Street is a major arterial route in Orange County, California running 15.6 miles (25.1 km) through the cities of Irvine, Santa Ana and Orange. Route description Main Street starts from West Yale Loop in the suburban area, Woodbridge in Irvine. From Culver Drive to Park Plaza, the route travels through the neighborhood, Westpark. From Jamboree Road to the California State Route 55 (SR 55), Main Street travels through Irvine Business Complex and nearby John Wayne Airport. At Sunflower Avenue in Santa Ana, Main Street becomes South Main Street and ends up on 1st Street and then becomes North Main Street to the Interstate 5 (I-5). At La Veta Avenue in Orange, North Main Street changes back to Main Street and through Orange and after Taft Avenue, Main Streets ends on Grove Avenue. Freeways that the route travels through *California State Route 55 (SR 55) *Interstate 5 (I-5) Freeways nearby * (I-405) *California State Route 57 (SR 57) Ends between There are 4 ends; North end, South end, East end and West end. In Irvine, Main Street has an East and West end. The East end is West Yale Loop and the West end is the California State Route 55 (SR 55). In between Santa Ana and Orange, Main Street has a South end and North end. The South end is Sunflower Avenue in Santa Ana and the North end is Grove Avenue in Orange.