Dr. Jay Yadav is an MD specializing in interventional cardiology. He is a prominent researcher and entrepreneur, widely known for his work as PI of the SAPPHIRE trial. Dr. Yadav designed the Angioguard embolic protection device used in the SAPPHIRE trial. he left the Cleveland Clinic in 2006 and is now associated with the Piedmont Heart Institute at Piedmont Hospital in Atlanta, Georgia, and is Chairman and CEO of Cardiomems, Inc. Departure from Cleveland Clinic In 2006, Dr. Yadav's position at the Cleveland Clinic was not renewed after an undisclosed conflict of interest was alleged, whereby he wrote "numerous" articles discussing SAPPHIRE or "prominently" mentioned Angioguard but did not disclose that he stood to gain from royalties if sales were increased. Dr. Yadav for his part states that he was unaware of the situation, having sold the device in 1999 and not reviewed the agreement in close detail. He stated that any proceeds that had been received would be donated to charity "to avoid even the appearance of impropriety."
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