Anyhoozle

Anyhoozle [IPA: ɛni-hoo-zɪl] is an American English slang adverb that is used to express a lack of concern as to advice, warning, hardship, etc. For example, if one were to advise, "You really ought to get a job" or "Just do the best you can", the response might be "Anyhoozle!".

Origin
The exclamation may have been originated on the Southwest Missouri State campus by N. Lefebvre. As a response to any advice she would receive, her response was, "Anyhoozle!"

Similar exclamations
Many other expressions in American English are synonyms of "Anyhoozle." "Anyways," and, "Regardless," are the most common.
 
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